Pradheep J. Shanker, M.D. Profile picture
Nov 19, 2022 14 tweets 3 min read Read on X
So, I didn't have any legal reason to not tell this story, but I had friends that were involved, and had no reason to get them into trouble.

With Elizabeth Holmes sentencing today, I think pretty much the entire story has come to a conclusion.

But the entire thing is sordid.
My tiny part? I was doing my fellowship in NYC. A childhood friend had a venture capital (he shall remain nameless; he has since made a tiny pot of gold). But his VC venture was affiliated with big players, including the likes of a guy from Omaha as well as people from Safeway.
He called me up specifically because they had gotten a request from a tiny company out of California called 'Real-Time Cures', that had a proposal that would change the medical industry!

It sounded like one of those elixirs from the 1800s.
I had, as they say, a very particular set of skills, as Liam Neeson would say. I had worked in labs studying microfluidics and biochemistry for analysis of serum samples.

In short...I kind of new what they were talking about.
At the time, my wife was expecting, I was in fellowship, we didn't have a ton of money...and my friend was going to throw me a few grand to go over the science here and tell them what I thought.

How could I refuse?
So, I got the documents they provided...and they were, to put it mildly, trash. They had no real data sets. Most of it was gibberish.

And I told my friend this.
But there were major people pushing this. So they offered me a little more money to join them on a meeting they were going to have with Dr. Roy, who was working with Holmes at the time (I never met Holmes).
In that meeting, I sat in the back, mostly because I was a nobody that was sleep deprived from being on call the night before ( I am not kidding).

But I got asked two questions. One was about the microfluidic technique, and was about the sample size.
Remember...I was sleep deprived! It is hilarious in hindsight. But I was annoyed, and basically said it was all bullshit.

I then got yelled at by some of the Theranos people for saying I didn't know what I was talking about. But I didn't care...I needed more coffee.
After the meeting, my friend and a couple of his colleagues (who represented a couple billionaires, but for the life of me I can't remember who) asked me again. I told them that it looked all fake to me. None of them invested.

The Safeway guys didn't ever talk to me.
Anyway, I took my check, and happily invested it in my son's college fund just after he was born, and didn't think about the entire thing for a LONG time.

Until about 2015, in fact. That was when John Ioannidis (of COVID fame) wrote this.

pubmed.ncbi.nlm.nih.gov/25688775/
Now, this was almost a decade later. And I had forgotten the whole thing. So I call my friend...and he laughed. Basically, he knew the entire thing was going to blow up at this point (the VC guys had caught wind finally). He did thank me for saving them a bunch of money though.
I never did hear from the Safeway guys. I later learned they lost something like a few hundred million dollars. And the irony is, if I had a better cup of coffee that morning, I might have been able to make a better argument and saved them that money. Oh well.
So, overall, I think I got paid around $10k for the entire thing? Maybe a little more. Anyway, I dumped that into my son's college fund, and its grown so much that it probably will pay for most of his college.

So Theranos, in a weird way, is going to fund my kid's education.

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More from @neoavatara

Apr 25
Here is what a lot of people don't understand about India/Pakistan...

Indians don't think about Pakistan until tragedy strikes.

Pakistan, on the other hand, is always focused on India.

This is a slightl oversimplification... But not a huge one.
India is focused on beginning a modern world power, that wants to be a leader amount the nations of the world. They have their regional problems, but that's not what drives them.

Pakistan wants to focus energy about Kashmir and other border disputes.
India's biggest threat is China.

But they want to join the US, Japan, Australia and the free nations of the world to counter their power.

Pakistan wants to be a Chinese vassal state.
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Apr 3
Almost makes you wonder how MAGA thinks we became the richest and most powerful country in the world.

Guess what: it wasn't because of our policies in the 50s, or even 60s.

American hegemony reached it peak AFTER THE 80s ...and beyond.

But these clowns can't answer why.
Don't believe me? Here you go:



In 1990, our per capita GDP was almost identical to Germany, France, UK, and Japan.

Today...we are MUCH HIGHER.

Why? MAGA can't answer this. ourworldindata.org/grapher/gdp-pe…Image
Here is another chart. Note that Japan was HIGHER than the US in 1988. That was when Trump used to complain about the trade deficit.

So what happened in between?

wits.worldbank.org/CountryProfile…Image
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Nov 7, 2024
Every couple decades or so, a political party complete deludes itself, is tone deaf, and then self immolates.

That is what the Democrats just did.

The fact they did this in the face of a threat from Trump just goes to show how stupid our political elites always are.
Trump won for a simple reason: He is politically smarter than Dems politically. Its the same reason Clinton, Bush, Obama won in the past; he is just better at politics than his opponents.
Trump should have never won in 2016, but stayed the course, and Hillary was stupid.

Trump would've won in 2020 if not for a once in a century global pandemic.

And this year, in the face of a mentally questionable President and a untrusted Vice President, easily won.
Read 13 tweets
Nov 6, 2024
Who is responsible for the Democrats' complete face plant?

5. DEI/Woke
4. Media
3. Antisemitic Left
2. Kamala Harris
1. Joe Biden
Nobody is more to blame than Joe Biden.

He promised to be a bridge to the future.

Instead in his arrogance he thought he could be a modern FDR, a transformative figure. What a joke.
Biden's failure to step aside, and to allow the Party to choose a successor, was a historic error, a selfish moment of personal privilege that cost the country greatly.

It is his legacy.
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Jun 24, 2024
My problem with Biden's response to the vast surge in antisemitism on his watch is that his statements have been fine, but followed up with almost zero specific action by his administration. He has done as little as Trump did after Charlottesville.
Frankly, Biden and AG Merrick Garland have acted far, FAR more aggressively against conservative groups.

See how they responded to critics of schools. They were right to do this...but we've seen nothing of the sort against anti-semites. Why?

apnews.com/article/educat…
Let's see Garland's 'memo' targeting anti-semitic groups, largely pro-Palestinian ones, and then I might believe they are treating this threat reasonably.

We've seen no such response.

Again, I rhetorically ask the question: Why?

We all know why.
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Jun 17, 2024
Democrats are really, truly going to be stupid enough to let Donald Trump win, aren't they?

They are completely oblivious and trying to lose.

Let me count the ways:
1. Biden's age.

This is pretty obvious at this point. They are denying the reality of Biden's physical and mental decline. Voters see it.
2. Polling

Biden himself has said that the polls 'were wrong'. They aren't wrong. They are probably relatively accurate. Best case scenario, Biden is tied with a convicted, impeached opponent. Worst case, he is losing to that same clown.
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